arsehole

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From Middle English arce-hoole, equivalent to arse + hole. Compare Old English ears-þyrel (“anus”, literally “arse-hole”).

Commonwealth, countable, mildly, uncountable, vulgar The anus. The moment I sat on the toilet, my crap immediately came out of my arsehole.
Commonwealth, countable, derogatory, mildly, offensive, uncountable An inconsiderate, mean-spirited, or otherwise contemptible person. (Less offensive than fucker or cunt.) Shut up, you big dummy! – Hey! Don't call me “big dummy”, you arsehole!
broadly, countable, uncountable, vulgar Anything (especially a place) that is unpleasant or undesirable. Welcome to [Town X], the arsehole of Britain.
Ireland, UK, uncountable, vulgar A variant of the card game big two.