indurate

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To harden or to grow hard. The ear, small and shapely, the arch of the foot, the curve in mouth and nostril, even the indurated hand dyed to the orange-tawny of the toucan's bill, a hand telling alike of the halyards and tar-bucket […] all this strangely indicated a lineage in direct contradiction to his lot.
To make callous or unfeeling. Oh, no ! it is the curse of revolutionary calamities to indurate the heart — the revolutionary impulse is too swift to admit of a pause at the sight of individual misery — the tempest is too loud to hear the wailings of the wretch that perishes beneath its billows […]
To inure; to strengthen; to make hardy or robust. The afternoon was not particularly warm: our noses and eyes were running; his were dry. He was evidently indurated against natural hardships.

Similar: inure

Hardened. The doctor removed a lot of indurate skin from his wound.
Obstinate, unfeeling, callous. Now are they indurate ⁊ tough as Pharao ⁊ will not bow vnto any ryghte waie oꝛ oꝛdꝛe.