systemic

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systemic

/sɪˈstɛm.ɪk/ UK
/sɪˈstiː.mɪk/ UK
/sɪˈstɛm.ɪk/ Canada, US
/sɪˈstem.ɪk/ Australia
/səˈstem.ək/ New Zealand
/ˈsɪs.ʈə.mɪk/ India
/sɪsˈʈɛː.mɪk/ India

Rhymes with -ɛmɪk, -iːmɪk, (India, also) -ɪk

Where it comes from

From system + -ic. Doublet of systematic.

adjective

not comparable Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society. We can learn from the incidents found it the project database - looking at them and understanding what happened and what might have been done differently. We can see past errors, including systemic issues that required attention at managerial levels.
not comparable Pertaining to an entire organism. Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).
Similar: holistic

Opposite: topical, endemic

Thesaurus

Closest in meaning: general, generalised, inherent, generalized, formal, systematic, systematically, methodical, overall, routine, pervasive, widespread, comprehensive, methodological, structured, methodology

adjective

Opposite: topical, endemic

Translations

Every language

adj relating to a system

Español	sistémico
Français	systémique
Deutsch	systemisch, System-
Русский	систе́мный sistémnyj
العربية	نِظَامِيّ niẓāmiyy

adj pertaining to an entire organism

Español	sistémico
Português	sistêmico
Français	systémique
Italiano	sistemico

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MLA

"systemic." Wiktionary, via Micwyn, micwyn.com/word/systemic. Accessed 6 Nov. 2026.

APA

systemic. (n.d.). In Wiktionary, via Micwyn. Retrieved November 6, 2026, from https://micwyn.com/word/systemic

Chicago

"systemic." Wiktionary, via Micwyn. Accessed November 6, 2026. https://micwyn.com/word/systemic.

BibTeX

@misc{systemic_2026,
  title = {systemic},
  howpublished = {Wiktionary, via Micwyn},
  year = {2026},
  url = {https://micwyn.com/word/systemic},
  urldate = {2026-11-06}
}